Professor Heneghen (carl heneghan), thank you for articulating the problem so well.

Arindam Basu

Oct 20, 2016·1 min read

Professor Heneghen (carl heneghan), thank you for articulating the problem so well. I’d say this is the most important well articulated position I read on EBHC in a long time.

The problem of unpublished trial results is wicked. We base our treatment decisions often on evidence that miss out on assimilating a body of evidence which is inherently incomplete, but that, I believe, is something we have to live with in foreseeable future. After reading this piece, if I may ask you, where you would put meta analyses? Are we compounding the problem?

Arindam Basu

Associate Professor of Epidemiology and Environmental Health at the University of Canterbury, New Zealand. Also in: https://refind.com/arinbasu

lled for all past and present clinical trials to be registe…ese problems are easier to fix than others; but they persist despite numerous attempts to fix them. For example, half of all trials never publish their results, leading to misleading effect sizes as positive trials are likely to be published twice as often as trials with negative results. To fix this AllTrials have called for all past and present clinical trials to be registered and th…

The crises in medical research and what to do about it

carl heneghan