Professor Heneghen (carl heneghan), thank you for articulating the problem so well. I’d say this is the most important well articulated position I read on EBHC in a long time.

The problem of unpublished trial results is wicked. We base our treatment decisions often on evidence that miss out on assimilating a body of evidence which is inherently incomplete, but that, I believe, is something we have to live with in foreseeable future. After reading this piece, if I may ask you, where you would put meta analyses? Are we compounding the problem?

Associate Professor of Epidemiology and Environmental Health at the University of Canterbury, New Zealand. Also in: https://refind.com/arinbasu

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